Submit Manuscript  

Article Details


Non-squamous Tumors of the Oropharynx and Oral Cavity: CT and MR Imaging Findings with Clinical- Pathologic Correlation

[ Vol. 13 , Issue. 2 ]

Author(s):

Antonello Vidiri, Davide Curione, Francesca Piludu, Antonino Guerrisi, Barbara Pichi, Giuseppe Mercante, Paolo Marchesi, Valentina Manciocco, Giuseppe Spriano and Renato Covello   Pages 166 - 175 ( 10 )

Abstract:


Non-squamous cell neoplasms (non-SCCs) are rare tumors of the oropharynx and oral cavity. They can be of many different histologic types, either benign or malignant, including in decreasing order of frequency minor salivary gland tumors, lymphoma, mesenchymal tumors, melanoma, and metastases. Unlike squamous cell carcinoma, non-SCCs could remain unidentified on clinical examination/endoscopy, because they usually manifest as submucosal masses without mucosal alterations. Diagnostic imaging, as CT and, more accurately, MR, plays an essential role in the work- up of these neoplasms, mainly in the staging and follow-up. Furthermore, radiologic features can, to a certain extent, help evaluate a lesion as more likely benign or malignant. More significantly, although generally non-specific, they can suggest or even allow the correct diagnosis in some cases, as pleomorphic adenoma, lymphoma, lipoma, hemangioma, neurofibroma, liposarcoma, and melanoma, especially if integrated with clinical/endoscopic findings and histologic knowledge. In this article, we illustrate CT and MR features of oropharyngeal and oral cavity non-SCCs taken from our experience, with clinical-histologic correlation, and review the literature on the topic.

Keywords:

Computed tomography (CT), diagnostic imaging, magnetic resonance (MR), non-squamous tumors (non-SCCs), oral cavity, oropharynx, pathology.

Affiliation:

Department of Radiology, Regina Elena National Cancer Institute, via Elio Chianesi 53, 00144, Rome, Department of Radiology, Catholic University of The Sacred Heart Agostino Gemelli Hospital, Rome, Department of Radiology, Regina Elena National Cancer Institute, Rome, Department of Radiology, Regina Elena National Cancer Institute, Rome, Department of Otolaryngology Head & Neck Surgery, Regina Elena National Cancer Institute, Rome, Department of Otolaryngology Head & Neck Surgery, Regina Elena National Cancer Institute, Rome, Department of Otolaryngology Head & Neck Surgery, Regina Elena National Cancer Institute, Rome, Department of Otolaryngology Head & Neck Surgery, Regina Elena National Cancer Institute, Rome, Department of Otolaryngology Head & Neck Surgery, Regina Elena National Cancer Institute, Rome, Department of Pathology, Regina Elena National Cancer Institute, Rome

Graphical Abstract:



Read Full-Text article