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Increased Radioisotope Accumulation Around Pulmonary Arteriovenous Fistula Illustrated by Tc-99m-macroaggregated Albumin Scintigraphy and SPECT/CT in a Patient with Osler-Weber-Rendu Syndrome

[ Vol. 14 , Issue. 1 ]

Author(s):

Shigeaki Higashiyama*, Joji Kawabe, Atsushi Yoshida, Kohei Kotani and Susumu Shiomi   Pages 151 - 153 ( 3 )

Abstract:


Tc-99m-MAA scintigraphy was performed in a patient with pulmonary hypertension to confirm the presence of a Right-to-LEFT (R-L) shunt due to the pulmonary Arteriovenous (AV) fistula. Both planar imaging and SPECT/CT showed multiple decreased or increased RI accumulation in both lung fields, and the R-L shunt ratio was high, indicating the presence of an R-L shunt. We considered that the decreased RI accumulated lesions were caused by pulmonary hypertension due to the pulmonary AV fistula. Osler-Weber-Rendu syndrome was proposed and genetic diagnosis was done. However, we speculated that the increased RI accumulated lesions were attributable to localized bleeding or a venous telangiectasia around the pulmonary AV fistula.

Keywords:

Osler-Weber-Rendu syndrome, pulmonary arteriovenous fistula, single-photon emission computed tomography/ computed tomography (SPECT/CT), Tc-99m-macroaggregated albumin (Tc-99m-MAA) scintigraphy, vascular malformations.

Affiliation:

Department of Nuclear Medicine, Osaka City University, Graduate School of Medicine, Osaka, Department of Nuclear Medicine, Osaka City University, Graduate School of Medicine, Osaka, Department of Nuclear Medicine, Osaka City University, Graduate School of Medicine, Osaka, Department of Nuclear Medicine, Osaka City University, Graduate School of Medicine, Osaka, Department of Nuclear Medicine, Osaka City University, Graduate School of Medicine, Osaka

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