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Clinical Value of 99mTc-octreotide Scintigraphy and Planar X-ray Mammography for the Diagnosis of Breast Cancer

[ Vol. 14 , Issue. 6 ]

Author(s):

Xiaojiang He, Jinxiong Huang, Guibing Chen, Hao Yu, Haojun Chen* and Yesen Li*   Pages 976 - 980 ( 5 )

Abstract:


Purpose: The purpose of this study was to compare the value of 99mTc-octreotide scintigraphy and planar X-ray mammography in the diagnosis of breast cancer.

Methods: A total of 65 patients with suspected breast cancer were enrolled. All patients underwent 99mTc-octreotide scintigraphy and planar X-ray mammography. The diagnostic efficiencies of 99mTc-octreotide scintigraphy and planar X-ray mammography were compared based on postsurgery pathology.

Results: The sensitivities of 99mTc-octreotide scintigraphy and planar X-ray mammography in the diagnosis of breast cancer were 90.6% and 66.0%, respectively. The specificities were 00% and 41.7%, while the accuracies were 91.4% and 66.7%, respectively. When 99mTc-octreotide scintigraphy was combined with planar X-ray mammography, the sensitivity, specificity, accuracy, positive predictive value, and negative predictive value for breast cancer were 96.2%, 100%, 94.1%, 87.9%, and 36.4%, respectively.

Conclusion: The diagnostic efficiency of 99mTc-octreotide scintigraphy for breast cancer is superior to that of planar X-ray mammography. When combined with planar X-ray mammography, the diagnostic efficiency of 99mTc-octreotide scintigraphy for breast cancer is further increased.

Keywords:

99mTc-octreotide scintigraphy, X-ray mammography, breast cancer, somatostatin, receptor, invasive ductal carcinoma.

Affiliation:

Department of Nuclear Medicine and Minnan PET Center, Xiamen Cancer Hospital, The First Affiliated Hospital of Xiamen University, Xiamen, Department of Nuclear Medicine and Minnan PET Center, Xiamen Cancer Hospital, The First Affiliated Hospital of Xiamen University, Xiamen, Department of Nuclear Medicine and Minnan PET Center, Xiamen Cancer Hospital, The First Affiliated Hospital of Xiamen University, Xiamen, Department of Nuclear Medicine and Minnan PET Center, Xiamen Cancer Hospital, The First Affiliated Hospital of Xiamen University, Xiamen, Department of Nuclear Medicine and Minnan PET Center, Xiamen Cancer Hospital, The First Affiliated Hospital of Xiamen University, Xiamen, Department of Nuclear Medicine and Minnan PET Center, Xiamen Cancer Hospital, The First Affiliated Hospital of Xiamen University, Xiamen

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