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Overview of Computer Aided Detection and Computer Aided Diagnosis Systems for Lung Nodule Detection in Computed Tomography


Shabana R. Ziyad*, V. Radha and Thavavel Vayyapuri   Pages 1 - 10 ( 10 )


Background : Lung cancer has become the major cause of cancer-related deaths. Detection of potentially malignant lung nodules is essential for the early diagnosis and clinical management of lung cancer. In clinical practice, the interpretation of Computed Tomography (CT) images is challenging for radiologists due to the large number of cases. There is a high rate of false positives in the manual findings. Computer aided detection system (CAD) and computer aided diagnosis systems (CADx) enhance the radiologists in accurately delineating the lung nodules.

Objective: The objective is to analyze CAD and CADx systems for lung nodule detection. It is necessary to review the various techniques followed in CAD and CADx systems proposed and implemented by various research persons. This study aims at analyzing the recent application of various concepts in computer science to each stage of CAD and CADx.

Method: This review paper is special in its own kind because it analyses the various techniques proposed by different eminent researchers in noise removal, contrast enhancement, thorax removal, lung segmentation, bone suppression, segmentation of trachea, classification of nodule and non-nodule and final classification of benign and malignant nodules.

Results: A comparison of performance of different techniques implemented by various researchers for the classification of nodule and non-nodule has been tabulated in the paper.

Conclusion: The findings of this review paper will definitely prove to be useful to the research community working on automation of lung nodule detection.


Lung Cancer, lung nodules, computed tomography, noise removal, lung segmentation, nodule classification


Department of Computer Science, College of Computer Engineering and Sciences, Prince Sattam Bin AbdulAziz University, Al Kharj, Department of Computer Science, Avinashilingam Institute for Home Science and Higher Education for Women, Coimbatore, Department Of Computer Science, College of Computer Engineering and Sciences, Prince Sattam Bin AbdulAziz University, Al Kharj

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