Submit Manuscript  

Article Details


Primary Breast Angiosarcoma: Utilisation of Pre-Surgical Magnetic Resonance Imaging (MRI) for Accurate Tumour Characterization and Planning – A Case Report and Literature Review

Author(s):

Nazimah Ab Mumin, Kartini Rahmat*, Marlina Tanty Ramli Hamid, Ng Wei Lin, Chan Wai Yee, Cheah Xin Ying, See Mee Hoong and Yip Cheng Har   Pages 1 - 7 ( 7 )

Abstract:


Background: Primary breast angiosarcoma is a rare malignancy with non-specific clinical and radiological findings. Case report: A 30-year-old lady presented with left breast pain and lumpiness over one year. She has had several breast ultrasounds (US) and was treated for acute mastitis and abscess. Subsequently, in view of the rapid growth of the lump and worsening pain, she was re-investigated with US, elastography, digital breast tomosynthesis (DBT) and MRI. MRI raised the suspicion of angiosarcoma. The diagnosis was confirmed after biopsy and she underwent mastectomy.

Discussion: Literature review on imaging findings of breast angiosarcoma especially on MRI is discussed. MRI features are heterogenous low signal intensity on T1 and high signal intensity in T2. Dynamic contrast enhancement (DCE) features are either early enhancement with or without washout in the delayed phase. Some reported central areas of nonenhancement.

Conclusion: This case report emphasises on the importance of MRI in clinching the diagnosis of breast angiosarcoma, and hence, should be offered sooner to prevent diagnostic delay.

Keywords:

Breast angiosarcoma, magnetic resonance imaging (MRI), ultrasound elastography, digital breast tomosynthesis(DBT), primary breast angiosarcoma, breast cancer

Affiliation:

Department of Biomedical Imaging, University of Malaya Research Imaging Centre, Kuala Lumpur, Department of Biomedical Imaging, University of Malaya Research Imaging Centre, Kuala Lumpur, Department of Biomedical Imaging, University of Malaya Research Imaging Centre, Kuala Lumpur, Department of Biomedical Imaging, University of Malaya Research Imaging Centre, Kuala Lumpur, Department of Biomedical Imaging, University of Malaya Research Imaging Centre, Kuala Lumpur, Department of Radiology, Hospital Sultan Ismail, Johor, Department of Surgery, University of Malaya Medical Centre, Kuala Lumpur, Department of Surgery, Subang Jaya Medical Centre, Kuala Lumpur



Read Full-Text article