Çisel Yazgan*, Hakan Ertürk and Ayşenaz Taşkın
Background: Behçet’s disease is a chronic multisystemic vasculitis affecting vessels of differing size in various organs. Thoracic manifestations of disease show wide spectrum involving a variety of anatomic structure within the chest. However, pulmonary artery involvement is a typical manifestation of disease that contributes significantly to mortality in patients. The study aimed to analyze CT features of thoracic manifestations, particularly pulmonary artery involvement, and to quantitatively assess bronchial arteries in Behçet’s disease.
Methods: Patients with Behçet’s disease who underwent CT scans for suspected thoracic involvement between 2010 and 2018 were included. CT findings of 52 patients were retrospectively analyzed for thoracic manifestations of the disease. Bronchial arteries were assessed regarding diameter in patients with/without pulmonary artery involvement. The pulmonary symptoms were noted.
Results: Of the 52 patients, 67% had thoracic manifestations including pulmonary artery involvement, parenchymal changes, superior vena cava thrombosis, and intracardiac thrombus. Pulmonary artery involvement was observed in 50% of the cohort. Peripheral pulmonary arteries (77%) were the most commonly affected branches, followed by lobar (42%) and central (35%) pulmonary arteries. Other thoracic findings were significantly correlated with pulmonary artery involvement (p<0.05). Compared to patients without pulmonary artery involvement, those with pulmonary artery involvement had a higher bronchial artery diameter (p<0.05) and occurrence rate of dilated bronchial arteries.
Conclusion: Involvement of peripheral pulmonary arteries is frequently encountered in Behçet’s disease and it can resemble pulmonary nodules. Dilated bronchial arteries, which can be observed in cases of pulmonary artery involvement, should be considered in patients with hemoptysis.
Behçet’s disease, imaging features, thoracic manifestation, pulmonary artery, computed tomography, hemoptysis.
Kastamonu University, Faculty of Medicine, Department of Radiology, Kastamonu,, Department of Radiology, Atatürk Chest Diseases and Chest Surgery Education and Research Hospital, 06280 Ankara,, Department of Chest Diseases, Atatürk Chest Diseases and Chest Surgery Education and Research Hospital, 06280 Ankara